Effects of endogenous morphine deprivation on memory retention of passive avoidance learning in mice
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چکیده
منابع مشابه
Effects of endogenous morphine deprivation on memory retention of passive avoidance learning in mice.
Memory and the processes of learning in mammals are well known to be affected by opioid agonists such as morphine, which has been proven to interfere and cause amnesia. The presence of endogenous morphine has been demonstrated in various tissues from mammals to invertebrates. In this study, we have investigated the effects caused by in-vivo immunodepletion of endogenous morphine on working memo...
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Background and purpose: Morphine as an opioid compound has different and sometimes conflicting effects on memory and learning process. Bile duct ligation causes cholestasis, which disrupts liver function. It is known that opioid systems are involved in cholestasis. The aim of this study was to investigate the possible effect of morphine on the memory of cholestatic rats. Materials and methods:...
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Introduction: Evidence indicates that morphine impairs memory process. Ghrelin hormone has been linked to learning and memory processes and modulates reward properties of addictive drugs. In this study we examined the role of middle septal ghrelin receptors in the effects of morphine on memory consolidation in passive avoidance learning. Materials & Methods: In this experimental study, 91 ma...
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Background and purpose: Many studies have reported the effect of morphine on memory impairment. Evidence suggests that ghrelin enhances memory consolidation. The median septum also has a major role in memory and learning mechanisms. The present study aimed at investigating the role of median septum on the effects of ghrelin in morphine-induced amnesia. Materials and methods: In this experiment...
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ژورنال
عنوان ژورنال: The International Journal of Neuropsychopharmacology
سال: 2004
ISSN: 1461-1457,1469-5111
DOI: 10.1017/s1461145704004341